In vivo targeting of miR‐223 in experimental eosinophilic oesophagitis
نویسندگان
چکیده
منابع مشابه
Eosinophilic oesophagitis: a clinical update.
British Journal of General Practice, September 2012 499 BACKGROUND Eosinophilic oeosophagitis (EoE) is a clinicopathological disease typified by eosinophilic infiltrate of the oesophageal epithelium, due to an allergic inflammatory response mediated by either food antigens or aeroallergens. The presence of eosinophils in the oesophagus has been recognised for a number of years since they were d...
متن کاملA case of adult eosinophilic oesophagitis
Background Adults with Eosinophilic Oesophagitis (EO) often present with a history of dysphagia and food impaction. Many are also atopic and sensitisation to foods is common; 81% of adults with EO in one study were sensitised to one or more food or inhalant allergen, and 50% had positive skin prick tests to one or more foods. Exclusion of foods has been reported to improve clinical symptoms; 94...
متن کاملEosinophilic oesophagitis: a novel treatment using Montelukast.
BACKGROUND Eosinophilic oesophagitis is a rarely diagnosed condition involving eosinophil infiltration of the oesophageal mucosa and creating significant symptoms of dysphagia. Failure to diagnose this disorder relates to reluctance to biopsy an apparently normal oesophagus. This is essential for histological diagnosis. To date, treatment success has been achieved only with corticosteroids. We ...
متن کاملEosinophilic oesophagitis: clinical presentation and pathogenesis
Eosinophilic oesophagitis (EoE) is an inflammatory disorder of the oesophagus which has become increasingly recognised over recent years, although it remains underdiagnosed in many centres. It is characterised histologically by a significant eosinophilic infiltration of the oesophageal mucosa (>15 eosinophils per high powered field), and clinically with features of oesophageal dysfunction such ...
متن کاملEosinophilic oesophagitis--a guide for primary care.
BACKGROUND Eosinophilic oesophagitis (EoE) is an increasingly recognised inflammatory disorder of the oesophagus. The incidence of this chronic, food-triggered disease is rising in Australia and diagnosis should be considered in patients who complain of dysphagia. OBJECTIVE This article provides an overview of the pathogenesis, evaluation and management of EoE. It is intended as a useful tool...
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ژورنال
عنوان ژورنال: Clinical & Translational Immunology
سال: 2020
ISSN: 2050-0068,2050-0068
DOI: 10.1002/cti2.1210